Life Science as Complex Systems: Constructive and inter-intra-dynamic
approach to development and evolution

Kunihiko KANEKO

The University of Tokyo

To demonstrate that a biological system is nothing but a kind of universal classes in open dynamical systems, the problems listed in the Table have been studied, both theoretically and experimentally. After presenting general standpoint of our approach, and surveying the current status, I will talk about theoretical studies on development and evolution. Irreversible loss of dynamic plasticity through the developmental process is discussed in terms of dynamical systems, while sympatric speciation as a compliance with interaction-induced phenotype differentiation is proposed.


construction of experiment theory question
replicating system replication in vitro from chemical reactions dynamics with few number of molecules origin of information; evolvebility
cell system replicating liposome with internal reaction recursive growth of autocatalytic reaction network condition for recursive growth
multi-cellular system interaction-induced differentiation of an ensemble of cells isologous diversification by inter-intra dynamics robustness & irrevrsibility in development
development artificial construction of tissues stem cell dynamics; pattern formation origin of positional information
generation germ-line from a cell ensemble recursive colony by adhesion difference origin of individuality
memory memory \& learning in a cell ensemble memory \& learning in dynamical systems irrevrsibility in control
evolution relevance of phenotypic differentiation symbiotic sympatric speciation fixation to symbols